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Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Retinoblastoma-Like Protein p130
Amino Acids, Peptides, and Proteins > Proteins > Phosphoproteins > Retinoblastoma-Like Protein p130
Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Tumor Suppressor Proteins > Retinoblastoma-Like Protein p130

Preferred term

Retinoblastoma-Like Protein p130  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • RBL2 Protein
  • Retinoblastoma Like Protein 2
  • Retinoblastoma-Like Protein 2
  • Retinoblastoma Like Protein p130

Scope note

  • A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. RBL2 contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and E2F5 TRANSCRIPTION FACTOR. RBL2 also interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.

History note

  • 2006(1994)

In other languages

URI

http://www.yso.fi/onto/mesh/D050717

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