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Concept information

Preferred term

Complement C1 Inhibitor Protein  

Type

  • Topical Descriptor

Entry terms

  • C1 Esterase Inhibitor
  • C1 Inhibitor Protein
  • C1-Inhibitor Protein
  • C1 INH Protein
  • C1-INH Protein
  • Complement C1-Inhibitor Protein
  • Esterase Inhibitor, C1
  • Plasma Protease C1 Inhibitor
  • Serpin Family G Member 1
  • Serpin G1
  • SERPING1

Note

  • do not confuse with COMPLEMENT C1 INACTIVATOR PROTEINS

Scope note

  • An endogenous 105-kDa plasma glycoprotein produced primarily by the LIVER and MONOCYTES. It inhibits a broad spectrum of proteases, including the COMPLEMENT C1R and the COMPLEMENT C1S proteases of the CLASSICAL COMPLEMENT PATHWAY, and the MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. C1-INH-deficient individuals suffer from HEREDITARY ANGIOEDEMA TYPES I AND II.

History note

  • 2006; for C1 ESTERASE INHIBITOR use COMPLEMENT C1 INACTIVATOR PROTEINS 1970-2005

In other languages

URI

http://www.yso.fi/onto/mesh/D050718

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