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Amino Acids, Peptides, and Proteins > Proteins > Cell Cycle Proteins > Cyclin-Dependent Kinase Inhibitor Proteins > Cyclin-Dependent Kinase Inhibitor p27
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Cyclin-Dependent Kinase Inhibitor Proteins > Cyclin-Dependent Kinase Inhibitor p27
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Cyclin-Dependent Kinase Inhibitor Proteins > Cyclin-Dependent Kinase Inhibitor p27
... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Tumor Suppressor Proteins > Cyclin-Dependent Kinase Inhibitor Proteins > Cyclin-Dependent Kinase Inhibitor p27

Preferred term

Cyclin-Dependent Kinase Inhibitor p27  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • CDK Inhibitor p27
  • CDK Inhibitor, p27
  • CDKN1B Protein
  • CDKN4 Protein
  • Cyclin Dependent Kinase Inhibitor 1B
  • Cyclin-Dependent Kinase Inhibitor 1B
  • Kip1 Protein, p27
  • p27 CDK Inhibitor
  • p27, CDK Inhibitor
  • p27 Kip1 Protein
  • p27Kip1 Protein

Scope note

  • A cyclin-dependent kinase inhibitor that coordinates the activation of CYCLIN and CYCLIN-DEPENDENT KINASES during the CELL CYCLE. It interacts with active CYCLIN D complexed to CYCLIN-DEPENDENT KINASE 4 in proliferating cells, while in arrested cells it binds and inhibits CYCLIN E complexed to CYCLIN-DEPENDENT KINASE 2.

History note

  • 2006(1992)

In other languages

URI

http://www.yso.fi/onto/mesh/D050760

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