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Concept information

Preferred term

Protoporphyrinogen Oxidase  

Type

  • Topical Descriptor

Entry terms

  • Dehydrogenase, Protoporphyrinogen
  • Oxidase, Protoporphyrinogen IX
  • Protoporphyrinogenase
  • Protoporphyrinogen Dehydrogenase
  • Protoporphyrinogen IX Oxidase
  • Protox

Scope note

  • A membrane-bound flavoenzyme that catalyzes the oxygen-dependent aromatization of protoporphyrinogen IX (Protogen) to protoporphyrin IX (Proto IX). It is the last enzyme of the common branch of the HEME and CHLOROPHYLL pathways in plants, and is the molecular target of diphenyl ether-type herbicides. VARIEGATE PORPHYRIA is an autosomal dominant disorder associated with deficiency of protoporphyrinogen oxidase.

History note

  • 2006(1975)

In other languages

URI

http://www.yso.fi/onto/mesh/D050768

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