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Concept information

Preferred term

Stathmin  

Type

  • Topical Descriptor

Entry terms

  • Lap18 Protein
  • Leukemia Associated Phosphoprotein p18
  • Leukemia-Associated Phosphoprotein p18
  • Metablastin
  • Oncoprotein 18
  • Op18 Phosphoprotein
  • p18, Leukemia-Associated Phosphoprotein
  • p18, Phosphoprotein
  • p19, Phosphoprotein
  • Phosphoprotein, Op18
  • Phosphoprotein p18
  • Phosphoprotein p19
  • Prosolin

Scope note

  • A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS.

History note

  • 2006(1987)

In other languages

  • Finnish

  • Swedish

  • Alfa-stathmin
  • Beta-stathmin
  • Metablastin
  • Onkoprotein 18
  • Prosolin

URI

http://www.yso.fi/onto/mesh/D050777

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