Concept information
Preferred term
STAT3 Transcription Factor
Type
-
Topical Descriptor
Broader concept
Entry terms
- Acute Phase Response Factor
- Acute-Phase Response Factor
- APRF Transcription Factor
- IL6 Response Factor
- IL6-Response Factor
- LIF Response Factor
- LIF-Response Factor
- Response Factor, Acute-Phase
- Signal Transducer and Activator of Transcription 3
- STAT3 Protein
- Transcription Factor, APRF
Scope note
- A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130.
History note
- 2006
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D050796
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