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Concept information

Preferred term

STAT3 Transcription Factor  

Type

  • Topical Descriptor

Entry terms

  • Acute Phase Response Factor
  • Acute-Phase Response Factor
  • APRF Transcription Factor
  • IL6 Response Factor
  • IL6-Response Factor
  • LIF Response Factor
  • LIF-Response Factor
  • Response Factor, Acute-Phase
  • Signal Transducer and Activator of Transcription 3
  • STAT3 Protein
  • Transcription Factor, APRF

Scope note

  • A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130.

History note

  • 2006

In other languages

URI

http://www.yso.fi/onto/mesh/D050796

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