Concept information
Preferred term
STAT5 Transcription Factor
Type
-
Topical Descriptor
Broader concept
Entry terms
- Signal Transducer and Activator of Transcription 5
- STAT5 Protein
Scope note
- A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA.
History note
- 2006(1992)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D050799
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