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Concept information

Preferred term

STAT5 Transcription Factor  

Type

  • Topical Descriptor

Entry terms

  • Signal Transducer and Activator of Transcription 5
  • STAT5 Protein

Scope note

  • A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA.

History note

  • 2006(1992)

In other languages

URI

http://www.yso.fi/onto/mesh/D050799

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