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Concept information

Preferred term

Interferon Regulatory Factors  

Type

  • Topical Descriptor

Entry terms

  • Factor, Interferon Regulatory
  • Interferon Regulatory Factor
  • IRF Transcription Factors
  • Regulatory Factor, Interferon
  • Transcription Factors, IRF

Scope note

  • A family of transcription factors that share an N-terminal HELIX-TURN-HELIX MOTIF and bind INTERFERON-inducible promoters to control GENE expression. IRF proteins bind specific DNA sequences such as interferon-stimulated response elements, interferon regulatory elements, and the interferon consensus sequence.

History note

  • 2006

URI

http://www.yso.fi/onto/mesh/D050835

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