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Concept information

Preferred term

Interferon Regulatory Factor-3  

Type

  • Topical Descriptor

Entry terms

  • IFN Regulatory Factor 3
  • IFN-Regulatory Factor 3
  • IRF 3 Transcription Factor
  • IRF-3 Transcription Factor
  • Transcription Factor, IRF-3

Scope note

  • An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.

History note

  • 2006(1996)

URI

http://www.yso.fi/onto/mesh/D050838

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