Concept information
Preferred term
Interferon Regulatory Factor-3
Type
-
Topical Descriptor
Broader concept
Entry terms
- IFN Regulatory Factor 3
- IFN-Regulatory Factor 3
- IRF 3 Transcription Factor
- IRF-3 Transcription Factor
- Transcription Factor, IRF-3
Scope note
- An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.
History note
- 2006(1996)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D050838
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