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Concept information

Preferred term

p300-CBP Transcription Factors  

Type

  • Topical Descriptor

Entry terms

  • Coactivator, p300-CBP
  • p300 CBP Coactivator
  • p300-CBP Coactivator
  • p300 CBP Protein
  • p300-CBP Protein

Scope note

  • A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. They function as transcriptional coactivators by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription machinery. They also modify transcription factors and CHROMATIN through ACETYLATION.

History note

  • 2006(1994)

URI

http://www.yso.fi/onto/mesh/D050880

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