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Concept information

Preferred term

Gene Fusion  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Note

  • ARTIFICIAL GENE FUSION is also available

Scope note

  • The GENETIC RECOMBINATION of the parts of two or more GENES resulting in a gene with different or additional regulatory regions, or a new chimeric gene product. ONCOGENE FUSION includes an ONCOGENE as at least one of the fusion partners and such gene fusions are often detected in neoplastic cells and are transcribed into ONCOGENE FUSION PROTEINS. ARTIFICIAL GENE FUSION is carried out in vitro by RECOMBINANT DNA technology.

History note

  • 2006

In other languages

URI

http://www.yso.fi/onto/mesh/D050939

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