Concept information
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Proteins
Intracellular Signaling Peptides and Proteins
Apoptosis Regulatory Proteins
Proto-Oncogene Proteins c-bcl-2
Preferred term
bcl-2-Associated X Protein
Type
-
Topical Descriptor
Broader concept
Entry terms
- Bax Apoptosis Regulator Protein
- Bax Protein
- bcl2 Associated X Protein
- bcl2-Associated X Protein
Note
- Don't confuse with the closely related BCL-X PROTEIN
Scope note
- A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein.
History note
- 2006(1993)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D051028
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