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Amino Acids, Peptides, and Proteins > Proteins > Flavoproteins > Apoptosis Inducing Factor
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Apoptosis Inducing Factor
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Apoptosis Inducing Factor
Enzymes and Coenzymes > Enzymes > Oxidoreductases > NADH, NADPH Oxidoreductases > Apoptosis Inducing Factor
Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Poly-ADP-Ribose Binding Proteins > Apoptosis Inducing Factor
Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Poly-ADP-Ribose Binding Proteins > Apoptosis Inducing Factor

Preferred term

Apoptosis Inducing Factor  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • AIF Apoptosis Regulatory Protein
  • Apoptosis-Inducing Factor
  • Apoptosis-Inducing Factor, Mitochondrial
  • Mitochondrial Apoptosis Inducing Factor
  • Mitochondrial Apoptosis-Inducing Factor

Note

  • INHIBITOR OF APOPTOSIS PROTEINS is also available

Scope note

  • A flavoprotein that functions as a powerful antioxidant in the MITOCHONDRIA and promotes APOPTOSIS when released from the mitochondria. In mammalian cells AIF is released in response to pro-apoptotic protein members of the bcl-2 protein family. It translocates to the CELL NUCLEUS and binds DNA to stimulate CASPASE-independent CHROMATIN condensation.

History note

  • 2006(1999)

In other languages

URI

http://www.yso.fi/onto/mesh/D051033

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