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Concept information

Preferred term

Inhibitor of Apoptosis Proteins  

Type

  • Topical Descriptor

Entry terms

  • Baculoviral Inhibitor Of Apoptosis Repeat Proteins
  • IAP Protein (Apoptosis)
  • IAP Repeat Containing Proteins
  • Inhibitor Of Apoptosis Protein
  • Inhibitor-Of-Apoptosis Protein

Note

  • APOPTOSIS REGULATORY PROTEINS is also available

Scope note

  • A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat; some members have ubiquitin-protein ligase activity.

History note

  • 2006(1997)

In other languages

URI

http://www.yso.fi/onto/mesh/D051034

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