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Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > PTEN Phosphohydrolase
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > PTEN Phosphohydrolase
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Phosphoric Monoester Hydrolases > PTEN Phosphohydrolase
Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Tumor Suppressor Proteins > PTEN Phosphohydrolase

Preferred term

PTEN Phosphohydrolase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • MMAC1 Protein
  • Mutated In Multiple Advanced Cancers 1 Protein
  • Phosphatase and Tensin Homologue on Chromosome Ten Protein
  • Phosphatase, PTEN
  • Phosphatase, PTEN Protein
  • Protein Phosphatase, PTEN
  • PTEN Phosphatase
  • PTEN Protein
  • PTEN Protein Phosphatase

Scope note

  • A lipid phosphatase that contains a C2 DOMAIN and acts on phosphatidylinositol-3,4,5-trisphosphate to regulate various SIGNAL TRANSDUCTION PATHWAYS. It modulates CELL GROWTH PROCESSES; CELL MIGRATION; and APOPTOSIS. Mutations in PTEN are associated with COWDEN DISEASE and PROTEUS SYNDROME as well as NEOPLASTIC CELL TRANSFORMATION.

History note

  • 2006(1997)

In other languages

URI

http://www.yso.fi/onto/mesh/D051059

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