Concept information
Preferred term
Wnt Proteins
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Factor, Wnt
- Protein, Wingless Type
- Protein, Wnt
- Type Protein, Wingless
- Wingless Type Protein
- Wingless Type Proteins
- Wnt Factor
- Wnt Factors
- Wnt Protein
Scope note
- Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.
History note
- 2006(1987)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D051153
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