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Concept information

Preferred term

Wnt Proteins  

Type

  • Topical Descriptor

Entry terms

  • Factor, Wnt
  • Protein, Wingless Type
  • Protein, Wnt
  • Type Protein, Wingless
  • Wingless Type Protein
  • Wingless Type Proteins
  • Wnt Factor
  • Wnt Factors
  • Wnt Protein

Scope note

  • Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.

History note

  • 2006(1987)

In other languages

URI

http://www.yso.fi/onto/mesh/D051153

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