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Concept information

Preferred term

Wiskott-Aldrich Syndrome Protein Family  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • WASP Protein Family
  • WAS Protein Family

Note

  • WISKOTT-ALDRICH SYNDROME PROTEIN and WISKOTT-ALDRICH SYNDROME PROTEIN, NEURONAL are also available

Scope note

  • A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.

History note

  • 2006(1999)

URI

http://www.yso.fi/onto/mesh/D051300

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