Concept information
Preferred term
Wiskott-Aldrich Syndrome Protein Family
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- WASP Protein Family
- WAS Protein Family
Note
- WISKOTT-ALDRICH SYNDROME PROTEIN and WISKOTT-ALDRICH SYNDROME PROTEIN, NEURONAL are also available
Scope note
- A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.
History note
- 2006(1999)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D051300
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