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Amino Acids, Peptides, and Proteins > Proteins > Cell Cycle Proteins > Cyclin-Dependent Kinases > Cyclin-Dependent Kinase 2
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Cyclin-Dependent Kinase 2
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Cyclin-Dependent Kinase 2
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Cyclin-Dependent Kinase 2

Preferred term

Cyclin-Dependent Kinase 2  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Cdc2 Related Protein Kinase
  • Cdc2-Related Protein Kinase
  • CDK2 Protein
  • Cdk2 Protein Kinase
  • p33cdk2 Kinase

Scope note

  • A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE and also interacts with CYCLIN A to phosphorylate RETINOBLASTOMA PROTEIN. Its activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P27 and CYCLIN-DEPENDENT KINASE INHIBITOR P21.

History note

  • 2006(1991)

In other languages

URI

http://www.yso.fi/onto/mesh/D051357

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