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Amino Acids, Peptides, and Proteins > Proteins > Cell Cycle Proteins > Cyclin-Dependent Kinases > Cyclin-Dependent Kinase 4
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Cyclin-Dependent Kinase 4
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Cyclin-Dependent Kinase 4
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Cyclin-Dependent Kinase 4

Preferred term

Cyclin-Dependent Kinase 4  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Cdk4 Cyclin Dependent Kinase
  • Cdk4 Cyclin-Dependent Kinase
  • Cdk4 Protein
  • Cdk4 Protein Kinase
  • Cell Division Protein Kinase 4
  • Cyclin D Dependent Kinase CDK4
  • Cyclin D-Dependent Kinase CDK4
  • Cyclin-Dependent Kinase, Cdk4
  • p34PSK J3 Kinase
  • p34PSK-J3 Kinase
  • Protein Kinase, Cdk4
  • PSK J3 Kinase
  • PSK-J3 Kinase

Scope note

  • Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16.

History note

  • 2006(1992)

In other languages

URI

http://www.yso.fi/onto/mesh/D051358

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