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Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Adaptor Proteins, Signal Transducing > GRB2 Adaptor Protein
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > GRB2 Adaptor Protein
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > GRB2 Adaptor Protein

Preferred term

GRB2 Adaptor Protein  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Abundant Src Homology Protein
  • Growth Factor Receptor Bound Protein 2
  • Growth Factor Receptor-Bound Protein-2

Scope note

  • A signal transducing adaptor protein that links extracellular signals to the MAP KINASE SIGNALING SYSTEM. Grb2 associates with activated EPIDERMAL GROWTH FACTOR RECEPTOR and PLATELET-DERIVED GROWTH FACTOR RECEPTORS via its SH2 DOMAIN. It also binds to and translocates the SON OF SEVENLESS PROTEINS through its SH3 DOMAINS to activate PROTO-ONCOGENE PROTEIN P21(RAS).

History note

  • 2006(1992)

In other languages

URI

http://www.yso.fi/onto/mesh/D051380

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