Concept information
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
Preferred term
Paxillin
Type
-
Topical Descriptor
Broader concept
Scope note
- Paxillin is a signal transducing adaptor protein that localizes to FOCAL ADHESIONS via its four LIM domains. It undergoes PHOSPHORYLATION in response to integrin-mediated CELL ADHESION, and interacts with a variety of proteins including VINCULIN; FOCAL ADHESION KINASE; PROTO-ONCOGENE PROTEIN PP60(C-SRC); and PROTO-ONCOGENE PROTEIN C-CRK.
History note
- 2006(1991)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D051419
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