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Concept information

Preferred term

Paxillin  

Type

  • Topical Descriptor

Scope note

  • Paxillin is a signal transducing adaptor protein that localizes to FOCAL ADHESIONS via its four LIM domains. It undergoes PHOSPHORYLATION in response to integrin-mediated CELL ADHESION, and interacts with a variety of proteins including VINCULIN; FOCAL ADHESION KINASE; PROTO-ONCOGENE PROTEIN PP60(C-SRC); and PROTO-ONCOGENE PROTEIN C-CRK.

History note

  • 2006(1991)

In other languages

URI

http://www.yso.fi/onto/mesh/D051419

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