Concept information
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Proteins
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
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Peptides
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
Preferred term
Receptor, Fibroblast Growth Factor, Type 2
Type
-
Topical Descriptor
Broader concept
Entry terms
- Antigen, CD332
- Bek Fgf Receptor Kinase
- BEK Fibroblast Growth Factor Receptor
- BEK Fibroblast Growth Factor Receptor Kinase
- BEK Protein Tyrosine Kinase
- Bek Related Fibroblast Growth Factor Receptor 1
- Bek-Related Fibroblast Growth Factor-Receptor-1
- CD332 Antigen
- FGFR2 Protein
- Fibroblast Growth Factor Receptor 2
- Fibroblast Growth Factor Receptors 2
Scope note
- A fibroblast growth factor receptor which contains three extracellular IMMUNOGLOBULIN I-SET DOMAINS and is expressed as two isoforms. One receptor isoform is expressed in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform is expressed mainly by EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME).
History note
- 2006(1999)
In other languages
URI
http://www.yso.fi/onto/mesh/D051497
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