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Concept information

Preferred term

Receptor, Fibroblast Growth Factor, Type 2  

Type

  • Topical Descriptor

Entry terms

  • Antigen, CD332
  • Bek Fgf Receptor Kinase
  • BEK Fibroblast Growth Factor Receptor
  • BEK Fibroblast Growth Factor Receptor Kinase
  • BEK Protein Tyrosine Kinase
  • Bek Related Fibroblast Growth Factor Receptor 1
  • Bek-Related Fibroblast Growth Factor-Receptor-1
  • CD332 Antigen
  • FGFR2 Protein
  • Fibroblast Growth Factor Receptor 2
  • Fibroblast Growth Factor Receptors 2

Scope note

  • A fibroblast growth factor receptor which contains three extracellular IMMUNOGLOBULIN I-SET DOMAINS and is expressed as two isoforms. One receptor isoform is expressed in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform is expressed mainly by EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME).

History note

  • 2006(1999)

URI

http://www.yso.fi/onto/mesh/D051497

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