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... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Protein Kinase C > Protein Kinase C-alpha
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Protein Kinase C > Protein Kinase C-alpha
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > Protein Kinase C > Protein Kinase C-alpha

Preferred term

Protein Kinase C-alpha  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • PKC alpha Serine Threonine Kinase
  • PKC-alpha Serine-Threonine Kinase
  • Protein Kinase C alpha
  • Protein Kinase C(alpha)
  • Serine-Threonine Kinase, PKC-alpha

Scope note

  • A cytoplasmic serine threonine kinase involved in regulating CELL DIFFERENTIATION and CELLULAR PROLIFERATION. Overexpression of this enzyme has been shown to promote PHOSPHORYLATION of BCL-2 PROTO-ONCOGENE PROTEINS and chemoresistance in human acute leukemia cells.

History note

  • 2006(1999)

In other languages

URI

http://www.yso.fi/onto/mesh/D051571

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