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Concept information

Preferred term

Activating Transcription Factor 6  

Type

  • Topical Descriptor

Entry terms

  • ATF6 Transcription Factor
  • Transcription Factor, ATF6

Scope note

  • One of the BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS that is synthesized as a membrane-bound protein in the ENDOPLASMIC RETICULUM. In response to endoplasmic reticulum stress it translocates to the GOLGI APPARATUS. It is activated by PROTEASES and then moves to the CELL NUCLEUS to regulate GENETIC TRANSCRIPTION of GENES involved in the unfolded protein response.

History note

  • 2006(1997)

URI

http://www.yso.fi/onto/mesh/D051702

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