Concept information
Preferred term
Host Cell Factor C1
Type
-
Topical Descriptor
Broader concept
Entry terms
- C1 Host Cell Factor
- Cell Proliferation Factor HCF
- HCFC1 Protein
Scope note
- A cellular transcriptional coactivator that contains N-terminal KELCH REPEATS and N- and C-terminal FIBRONECTIN TYPE III DOMAINS. It functions as a transcription factor for a number of genes and in the assembly of IMMEDIATE-EARLY PROTEINS of the HERPES SIMPLEX VIRUS. Mutations in the HCFC1 gene are associated with cases of X-LINKED MENTAL RETARDATION.
History note
- 2006(1995)
In other languages
-
Finnish
URI
http://www.yso.fi/onto/mesh/D051863
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