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Concept information

Preferred term

Host Cell Factor C1  

Type

  • Topical Descriptor

Entry terms

  • C1 Host Cell Factor
  • Cell Proliferation Factor HCF
  • HCFC1 Protein

Scope note

  • A cellular transcriptional coactivator that contains N-terminal KELCH REPEATS and N- and C-terminal FIBRONECTIN TYPE III DOMAINS. It functions as a transcription factor for a number of genes and in the assembly of IMMEDIATE-EARLY PROTEINS of the HERPES SIMPLEX VIRUS. Mutations in the HCFC1 gene are associated with cases of X-LINKED MENTAL RETARDATION.

History note

  • 2006(1995)

In other languages

URI

http://www.yso.fi/onto/mesh/D051863

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