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Concept information

Preferred term

Receptors, Notch  

Type

  • Topical Descriptor

Entry terms

  • Notch Protein
  • Notch Proteins
  • Notch Receptor
  • Notch Receptors
  • Protein, Notch
  • Receptor, Notch

Scope note

  • A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN REPEATS in their cytoplasmic domains. The cytoplasmic domains are released upon ligand binding and translocate to the CELL NUCLEUS, where they act as transcription factors.

History note

  • 2006(1990)

In other languages

URI

http://www.yso.fi/onto/mesh/D051880

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