Concept information
Preferred term
Receptors, Notch
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Notch Protein
- Notch Proteins
- Notch Receptor
- Notch Receptors
- Protein, Notch
- Receptor, Notch
Scope note
- A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN REPEATS in their cytoplasmic domains. The cytoplasmic domains are released upon ligand binding and translocate to the CELL NUCLEUS, where they act as transcription factors.
History note
- 2006(1990)
In other languages
-
Finnish
-
Swedish
-
Receptorer, notch
URI
http://www.yso.fi/onto/mesh/D051880
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