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Biological Factors > Immune Checkpoint Proteins > B7-2 Antigen
Amino Acids, Peptides, and Proteins > Proteins > Immune Checkpoint Proteins > B7-2 Antigen
Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > B7 Antigens > B7-2 Antigen
Biological Factors > Intercellular Signaling Peptides and Proteins > B7 Antigens > B7-2 Antigen
Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > B7 Antigens > B7-2 Antigen
Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > B7 Antigens > B7-2 Antigen
Biological Factors > Antigens > Antigens, Surface > B7 Antigens > B7-2 Antigen

Preferred term

B7-2 Antigen  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Antigen, B7 2
  • Antigen, B7-2
  • Antigen, CD86
  • Antigens, CD86
  • B70 Costimulatory Molecule
  • B7-2 Costimulatory Molecule
  • CD86 Antigen
  • CD86 Antigens
  • Costimulatory Molecule, B70
  • Costimulatory Molecule, B7-2
  • Early T Cell Costimulatory Molecule 1

Scope note

  • A costimulatory ligand glycoprotein that contains a C2 and V-type IMMUNOGLOBULIN DOMAIN. It is expressed by ANTIGEN-PRESENTING CELLS and binds to CD28 ANTIGEN with high specificity and to CTLA-4 ANTIGEN with low specificity. The interaction of CD86 with CD28 ANTIGEN provides a stimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.

History note

  • 2018 (1993)

In other languages

URI

http://www.yso.fi/onto/mesh/D051940

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