Concept information
Preferred term
Pore Forming Cytotoxic Proteins
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Scope note
- Proteins secreted from an organism which form membrane-spanning pores in target cells to destroy them. This is in contrast to PORINS and MEMBRANE TRANSPORT PROTEINS that function within the synthesizing organism and COMPLEMENT immune proteins. These pore forming cytotoxic proteins are a form of primitive cellular defense which are also found in human LYMPHOCYTES.
History note
- 2007
In other languages
URI
http://www.yso.fi/onto/mesh/D052899
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