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... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Adaptor Proteins, Signal Transducing > Death Domain Receptor Signaling Adaptor Proteins > Caspase 8
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Death Domain Receptor Signaling Adaptor Proteins > Caspase 8
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Death Domain Receptor Signaling Adaptor Proteins > Caspase 8
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Death Domain Receptor Signaling Adaptor Proteins > Caspase 8
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Death Domain Receptor Signaling Adaptor Proteins > Caspase 8
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Caspases > Caspases, Initiator > Caspase 8
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Caspases > Caspases, Initiator > Caspase 8
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Cysteine Endopeptidases > Caspases > Caspases, Initiator > Caspase 8
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Cysteine Proteases > Cysteine Endopeptidases > Caspases > Caspases, Initiator > Caspase 8

Preferred term

Caspase 8  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • CAP4 Protease
  • Caspase-8
  • FLICE Protein
  • MACH Protein
  • Mch5 Protease

Scope note

  • A long pro-domain caspase that contains a death effector domain in its pro-domain region. Caspase 8 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS.

History note

  • 2007(2000)

In other languages

URI

http://www.yso.fi/onto/mesh/D053181

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