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Concept information

Preferred term

Fas-Associated Death Domain Protein  

Type

  • Topical Descriptor

Entry terms

  • FADD, Fas-Associating Protein
  • FADD Protein, Fas Associating
  • FADD Protein, Fas-Associating
  • Fas Associated Death Domain Protein
  • Fas-Associating FADD Protein
  • Fas Associating Protein FADD
  • Fas-Associating Protein FADD
  • Fas Associating Protein with Death Domain
  • Fas-Associating Protein with Death Domain
  • MORT1 Protein

Scope note

  • A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a death effector domain that can interact with death effector domains found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES via interaction with this protein plays a role in the signaling cascade that leads to APOPTOSIS.

History note

  • 2007(1995)

In other languages

URI

http://www.yso.fi/onto/mesh/D053200

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