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Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Death Domain

Preferred term

Receptors, Death Domain  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • Death Domain Receptors
  • Death Receptor
  • Death Receptors
  • DR Family Receptors
  • Receptor, Death
  • Receptors, Death Domain Family
  • Receptors, DR Family

Scope note

  • A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a DEATH DOMAIN due to the fact that many of these receptors are involved in APOPTOSIS signaling pathways. Several DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as CASPASES.

History note

  • 2007

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URI

http://www.yso.fi/onto/mesh/D053218

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