Concept information
Preferred term
TNF-Related Apoptosis-Inducing Ligand
Type
-
Topical Descriptor
Broader concept
Entry terms
- Antigen, CD253
- Apo 2 Ligand
- Apo-2 Ligand
- Apo 2L Protein
- Apo-2L Protein
- CD253 Antigen
- TNF Superfamily, Member 10
- TRAIL Protein
- Tumor Necrosis Factor Ligand Superfamily Member 10
Scope note
- A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form.
History note
- 2007(2005)
In other languages
URI
http://www.yso.fi/onto/mesh/D053221
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}