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Concept information

Preferred term

Fas Ligand Protein  

Type

  • Topical Descriptor

Entry terms

  • Antigen, CD178
  • Antigens, CD178
  • CD178 Antigen
  • CD178 Antigens
  • CD95 Antigen Ligand
  • CD95L
  • CD95 Ligand
  • Fas Ligand
  • Fas Ligand (FasL)
  • FasL Protein
  • TNF Superfamily, Member 6
  • Tumor Necrosis Factor Ligand Superfamily Member 6

Scope note

  • A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.

History note

  • 2007(1994)

In other languages

URI

http://www.yso.fi/onto/mesh/D053222

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