Concept information
Preferred term
Fas Ligand Protein
Type
-
Topical Descriptor
Broader concept
Entry terms
- Antigen, CD178
- Antigens, CD178
- CD178 Antigen
- CD178 Antigens
- CD95 Antigen Ligand
- CD95L
- CD95 Ligand
- Fas Ligand
- Fas Ligand (FasL)
- FasL Protein
- TNF Superfamily, Member 6
- Tumor Necrosis Factor Ligand Superfamily Member 6
Scope note
- A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.
History note
- 2007(1994)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D053222
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