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Concept information

Preferred term

Receptors, Tumor Necrosis Factor, Member 14  

Type

  • Topical Descriptor

Entry terms

  • Entry Mediator, Herpesvirus
  • Herpesvirus Entry Mediator
  • HveA Protein
  • HVEM Protein
  • Tumor Necrosis Factor Receptor Subfamily, Member 14
  • Tumor Necrosis Factor Receptor Superfamily, Member 14

Scope note

  • A novel member of the tumor-necrosis factor receptor family that can also mediate HERPES SIMPLEX VIRUS TYPE 1 entry into cells. It has specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 and the homotrimeric form of LYMPHOTOXIN-ALPHA. The receptor is abundantly expressed on T-LYMPHOCYTES and may play a role in regulating lymphocyte activation. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.

History note

  • 2007(1997)

In other languages

URI

http://www.yso.fi/onto/mesh/D053240

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