Concept information
Preferred term
Receptors, Tumor Necrosis Factor, Member 14
Type
-
Topical Descriptor
Broader concept
Entry terms
- Entry Mediator, Herpesvirus
- Herpesvirus Entry Mediator
- HveA Protein
- HVEM Protein
- Tumor Necrosis Factor Receptor Subfamily, Member 14
- Tumor Necrosis Factor Receptor Superfamily, Member 14
Scope note
- A novel member of the tumor-necrosis factor receptor family that can also mediate HERPES SIMPLEX VIRUS TYPE 1 entry into cells. It has specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 and the homotrimeric form of LYMPHOTOXIN-ALPHA. The receptor is abundantly expressed on T-LYMPHOCYTES and may play a role in regulating lymphocyte activation. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
History note
- 2007(1997)
In other languages
-
Finnish
-
TNF-reseptori, jäsen 14
-
Swedish
URI
http://www.yso.fi/onto/mesh/D053240
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