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Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Cytokine > Receptors, Tumor Necrosis Factor > Tumor Necrosis Factor Decoy Receptors > Osteoprotegerin

Preferred term

Osteoprotegerin  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • FDCR 1 Protein
  • FDCR-1 Protein
  • Follicular Dendritic Cell Derived Receptor 1
  • Follicular Dendritic Cell-Derived Receptor-1
  • OCIF Protein
  • Osteoclastogenesis Inhibitory Factor
  • Receptors, Tumor Necrosis Factor, Member 11b
  • Tumor Necrosis Factor Receptor 11b
  • Tumor Necrosis Factor Receptor Superfamily, Member 11b

Scope note

  • A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.

History note

  • 2007(1997)

In other languages

URI

http://www.yso.fi/onto/mesh/D053244

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