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Concept information

Preferred term

Apolipoprotein C-II  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • ApoC2
  • Apo C II
  • Apo C-II
  • Apolipoprotein C 2
  • Apolipoprotein C-2
  • Apolipoprotein CII
  • Apoprotein C II
  • Apoprotein C-II

Scope note

  • A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS. It contains a cofactor for LIPOPROTEIN LIPASE and activates several triacylglycerol lipases. The association of Apo C-II with plasma CHYLOMICRONS; VLDL, and HIGH-DENSITY LIPOPROTEINS is reversible and changes rapidly as a function of triglyceride metabolism. Clinically, Apo C-II deficiency is similar to lipoprotein lipase deficiency (HYPERLIPOPROTEINEMIA TYPE I) and is therefore called hyperlipoproteinemia type IB.

History note

  • 2007; use APOLIPOPROTEIN C-II (NM) 1978-2006

In other languages

URI

http://www.yso.fi/onto/mesh/D053304

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