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Lipids > Lipoproteins > Apolipoproteins > Apolipoproteins C > Apolipoprotein C-III
... > Amino Acids, Peptides, and Proteins > Proteins > Lipoproteins > Apolipoproteins > Apolipoproteins C > Apolipoprotein C-III
... > Amino Acids, Peptides, and Proteins > Proteins > Apoproteins > Apolipoproteins > Apolipoproteins C > Apolipoprotein C-III

Preferred term

Apolipoprotein C-III  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Apo C III
  • Apo C-III
  • Apolipoprotein CIII

Scope note

  • A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS and CHYLOMICRON REMNANTS. Apo C-III, synthesized in the liver, is an inhibitor of LIPOPROTEIN LIPASE. Apo C-III modulates the binding of chylomicron remnants and VLDL to receptors (RECEPTORS, LDL) thus decreases the uptake of triglyceride-rich particles by the liver cells and subsequent degradation. The normal Apo C-III is glycosylated. There are several polymorphic forms with varying amounts of SIALIC ACID (Apo C-III-0, Apo C-III-1, and Apo C-III-2).

History note

  • 2007; use APOLIPOPROTEIN C-III (NM) 1979-2006

In other languages

URI

http://www.yso.fi/onto/mesh/D053305

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