Concept information
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Proteins
Carrier Proteins
Adaptor Proteins, Signal Transducing
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
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Proteins
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
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Peptides
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
...
Proteins
Carrier Proteins
Adaptor Proteins, Signal Transducing
Death Domain Receptor Signaling Adaptor Proteins
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Proteins
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
Death Domain Receptor Signaling Adaptor Proteins
...
Peptides
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
Death Domain Receptor Signaling Adaptor Proteins
Preferred term
Edar-Associated Death Domain Protein
Type
-
Topical Descriptor
Broader concept
Entry terms
- Edaradd Protein
Scope note
- A tumor necrosis factor receptor-associated factor that acts as a specific signaling adaptor protein for the EDAR RECEPTOR and plays an important role in ectodermal development. It binds to edar receptor via its C-terminal death domain region and to other specific TNF receptor-associated factors via its N-terminal domain. Loss of function of edar-associated death domain protein is associated with AUTOSOMAL RECESSIVE ANHIDROTIC ECTODERMAL DYSPLASIA.
History note
- 2007(2002)
In other languages
-
Finnish
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Swedish
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Edaradd-protein
URI
http://www.yso.fi/onto/mesh/D053362
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