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Concept information

Preferred term

Receptor-Interacting Protein Serine-Threonine Kinases  

Type

  • Topical Descriptor

Entry terms

  • Kinases, RIP Serine-Threonine
  • RIP Serine Threonine Kinases
  • RIP Serine-Threonine Kinases
  • Serine-Threonine Kinases, RIP

Scope note

  • A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.

History note

  • 2007(1995)

URI

http://www.yso.fi/onto/mesh/D053422

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