Concept information
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Proteins
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
CARD Signaling Adaptor Proteins
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Peptides
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
CARD Signaling Adaptor Proteins
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Proteins
Intracellular Signaling Peptides and Proteins
Apoptosis Regulatory Proteins
CARD Signaling Adaptor Proteins
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Peptides
Intracellular Signaling Peptides and Proteins
Apoptosis Regulatory Proteins
CARD Signaling Adaptor Proteins
...
Intracellular Signaling Peptides and Proteins
Apoptosis Regulatory Proteins
Caspases
Caspases, Initiator
Preferred term
Caspase 9
Type
-
Topical Descriptor
Broader concept
Entry terms
- Apoptotic Protease Activating Factor 3
- Caspase-9
- ICE LAP6 Protein
- ICE-LAP6 Protein
- ICE Like Apoptotic Protease 6
- ICE-Like Apoptotic Protease 6
Note
- Do not confuse with CAS9 ENZYME see CRISPR-ASSOCIATED PROTEIN 9
Scope note
- A long pro-domain caspase that contains a CASPASE RECRUITMENT DOMAIN in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.
History note
- 2007(2005)
In other languages
-
Finnish
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Swedish
URI
http://www.yso.fi/onto/mesh/D053453
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