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Concept information

Preferred term

Caspase 9  

Type

  • Topical Descriptor

Entry terms

  • Apoptotic Protease Activating Factor 3
  • Caspase-9
  • ICE LAP6 Protein
  • ICE-LAP6 Protein
  • ICE Like Apoptotic Protease 6
  • ICE-Like Apoptotic Protease 6

Note

  • Do not confuse with CAS9 ENZYME see CRISPR-ASSOCIATED PROTEIN 9

Scope note

  • A long pro-domain caspase that contains a CASPASE RECRUITMENT DOMAIN in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.

History note

  • 2007(2005)

In other languages

URI

http://www.yso.fi/onto/mesh/D053453

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