Concept information
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Intracellular Signaling Peptides and Proteins
Apoptosis Regulatory Proteins
Caspases
Caspases, Initiator
Preferred term
Caspase 12
Type
-
Topical Descriptor
Broader concept
Entry terms
- Caspase-12
Scope note
- A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 12 is activated by pro-apoptotic factors that are released during cell stress and by CARD SIGNALING ADAPTOR PROTEINS. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.
History note
- 2007(2000)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D053454
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