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Concept information

Preferred term

Caspase 12  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Caspase-12

Scope note

  • A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 12 is activated by pro-apoptotic factors that are released during cell stress and by CARD SIGNALING ADAPTOR PROTEINS. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.

History note

  • 2007(2000)

In other languages

URI

http://www.yso.fi/onto/mesh/D053454

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