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Concept information

Preferred term

Caspase 10  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Caspase-10

Scope note

  • A long pro-domain caspase that contains a death effector domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS. Caspase 10 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.

History note

  • 2007(1998)

In other languages

URI

http://www.yso.fi/onto/mesh/D053455

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