Concept information
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Intracellular Signaling Peptides and Proteins
Apoptosis Regulatory Proteins
Caspases
Caspases, Initiator
Preferred term
Caspase 10
Type
-
Topical Descriptor
Broader concept
Entry terms
- Caspase-10
Scope note
- A long pro-domain caspase that contains a death effector domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS. Caspase 10 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
History note
- 2007(1998)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D053455
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