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... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Caspases > Caspases, Initiator
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Caspases > Caspases, Initiator
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Cysteine Endopeptidases > Caspases > Caspases, Initiator
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Cysteine Proteases > Cysteine Endopeptidases > Caspases > Caspases, Initiator

Preferred term

Caspases, Initiator  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Initiator Caspases

Scope note

  • A subtype of caspases that contain long pro-domain regions that regulate the activation of the enzyme. The pro-domain regions contain protein-protein interaction motifs that can interact with specific signaling adaptor proteins such as DEATH DOMAIN RECEPTORS; DED SIGNALING ADAPTOR PROTEINS; and CARD SIGNALING ADAPTOR PROTEINS. Once activated, the initiator caspases can activate other caspases such as the EFFECTOR CASPASES.

History note

  • 2007

In other languages

URI

http://www.yso.fi/onto/mesh/D053471

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