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... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Adaptor Proteins, Signal Transducing > CARD Signaling Adaptor Proteins > Nod2 Signaling Adaptor Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > CARD Signaling Adaptor Proteins > Nod2 Signaling Adaptor Protein
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > CARD Signaling Adaptor Proteins > Nod2 Signaling Adaptor Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > CARD Signaling Adaptor Proteins > Nod2 Signaling Adaptor Protein
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > CARD Signaling Adaptor Proteins > Nod2 Signaling Adaptor Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Adaptor Proteins, Signal Transducing > Nod Signaling Adaptor Proteins > Nod2 Signaling Adaptor Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Nod Signaling Adaptor Proteins > Nod2 Signaling Adaptor Protein
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Nod Signaling Adaptor Proteins > Nod2 Signaling Adaptor Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > NLR Proteins > Nod Signaling Adaptor Proteins > Nod2 Signaling Adaptor Protein
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > NLR Proteins > Nod Signaling Adaptor Proteins > Nod2 Signaling Adaptor Protein

Preferred term

Nod2 Signaling Adaptor Protein  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • CARD15 Protein
  • Caspase Recruitment Domain Protein 15
  • Nucleotide Oligomerization Domain 2 Protein

Scope note

  • A NOD signaling adaptor protein that contains two C-terminal leucine-rich domains which recognize bacterial PEPTIDOGLYCAN. It signals via an N-terminal capase recruitment domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE KINASES. The protein plays a role in the host defense response by signaling the activation of CASPASES and the MAP KINASE SIGNALING SYSTEM. Mutations of the gene encoding the nucleotide oligomerization domain 2 protein have been associated with increased susceptibility to CROHN DISEASE.

History note

  • 2007

In other languages

URI

http://www.yso.fi/onto/mesh/D053473

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