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Concept information

Preferred term

Nod1 Signaling Adaptor Protein  

Type

  • Topical Descriptor

Entry terms

  • CARD4 Protein
  • Caspase Recruitment Domain Protein 4
  • Nucleotide Oligomerization Domain 1 Protein

Scope note

  • A NOD-signaling adaptor protein that contains a C-terminal leucine-rich domain which recognizes bacterial PEPTIDOGLYCAN. It signals via an N-terminal caspase recruitment domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE KINASES. It plays a role in the host defense response by signaling the activation of CASPASES and the MAP KINASE SIGNALING SYSTEM.

History note

  • 2007

In other languages

URI

http://www.yso.fi/onto/mesh/D053474

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