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... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Adaptor Proteins, Signal Transducing > CARD Signaling Adaptor Proteins > Apoptotic Protease-Activating Factor 1
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > CARD Signaling Adaptor Proteins > Apoptotic Protease-Activating Factor 1
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > CARD Signaling Adaptor Proteins > Apoptotic Protease-Activating Factor 1
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > CARD Signaling Adaptor Proteins > Apoptotic Protease-Activating Factor 1
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > CARD Signaling Adaptor Proteins > Apoptotic Protease-Activating Factor 1

Preferred term

Apoptotic Protease-Activating Factor 1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Apaf 1 Protease Activating Factor
  • Apaf-1 Protease-Activating Factor
  • Apoptotic Peptidase Activating Factor 1
  • Protease-Activating Factor, Apaf-1

Scope note

  • A CARD signaling adaptor protein characterized by an N-terminal CARD DOMAIN and C-terminal WD40 REPEATS. It plays a role in the mitochondria-stimulated apoptosis (APOPTOSIS, INTRINSIC PATHWAY) and binds to CYTOCHROME C in the CYTOSOL to form an APOPTOSOMAL PROTEIN COMPLEX which activates INITIATOR CASPASES such as CASPASE 9.

History note

  • 2007(1997)

In other languages

URI

http://www.yso.fi/onto/mesh/D053477

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