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Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Cytokine > Receptors, Interleukin > Receptors, Interleukin-1 > Interleukin-1 Receptor Accessory Protein

Preferred term

Interleukin-1 Receptor Accessory Protein  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • IL-1RAcP

Note

  • Do not confuse with INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN

Scope note

  • A protein that takes part in the formation of active interleukin-1 receptor complex. It binds specifically to INTERLEUKIN-1 and the INTERLEUKIN-1 RECEPTOR TYPE I at the cell surface to form a heterotrimeric complex that brings its cytoplasmic domain into contact with the cytoplasm domain of the TYPE-I INTERLEUKIN-1 RECEPTOR. Activation of intracellular signal transduction pathways from the receptor is believed to be driven by this form of cytoplasmic interaction.

History note

  • 2007(1996)

In other languages

URI

http://www.yso.fi/onto/mesh/D053577

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