Concept information
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Preferred term
Janus Kinases
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- JAK Kinases
- Janus Kinase
- Kinase, Janus
- Kinases, JAK
Scope note
- A family of intracellular tyrosine kinases that participate in the signaling cascade of cytokines by associating with specific CYTOKINE RECEPTORS. They act upon STAT TRANSCRIPTION FACTORS in signaling pathway referred to as the JAK/STAT pathway. The name Janus kinase refers to the fact the proteins have two phosphate-transferring domains.
History note
- 2007
In other languages
-
Finnish
-
Janus-kinaasi
-
Swedish
URI
http://www.yso.fi/onto/mesh/D053612
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