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... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Oncogene Proteins > Proto-Oncogene Proteins > Janus Kinase 2
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Janus Kinases > Janus Kinase 2
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Janus Kinases > Janus Kinase 2
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein-Tyrosine Kinases > Janus Kinases > Janus Kinase 2

Preferred term

Janus Kinase 2  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • JAK 2 Protein Tyrosine Kinase
  • JAK-2 Protein Tyrosine Kinase
  • JAK2 Protein Tyrosine Kinase

Scope note

  • A Janus kinase subtype that is involved in signaling from GROWTH HORMONE RECEPTORS; PROLACTIN RECEPTORS; and a variety of CYTOKINE RECEPTORS such as ERYTHROPOIETIN RECEPTORS and INTERLEUKIN RECEPTORS. Dysregulation of Janus kinase 2 due to GENETIC TRANSLOCATIONS have been associated with a variety of MYELOPROLIFERATIVE DISORDERS.

History note

  • 2007(1992)

In other languages

URI

http://www.yso.fi/onto/mesh/D053614

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