Concept information
Preferred term
Receptor, Interferon alpha-beta
Type
-
Topical Descriptor
Broader concept
Entry terms
- alpha Receptor, Interferon
- alpha Receptors, Interferon
- IFN alphabetaR
- IFN-alphabetaR
- IFN-alphaR
- Interferon alpha beta Receptor
- Interferon alpha-beta Receptor
- Interferon alphabeta Receptors
- Interferon alpha Receptor
- Interferon alpha Receptors
- Receptor, Interferon alpha
- Receptors, Interferon alpha
- Receptors, Interferon alphabeta
- Type I Interferon Receptor
Scope note
- A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE.
History note
- 2007(1993)
In other languages
-
Finnish
-
Swedish
-
Interferon alfa-receptor
-
Typ II interferonreceptor
URI
http://www.yso.fi/onto/mesh/D053633
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