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Concept information

Preferred term

Receptor, Interferon alpha-beta  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • alpha Receptor, Interferon
  • alpha Receptors, Interferon
  • IFN alphabetaR
  • IFN-alphabetaR
  • IFN-alphaR
  • Interferon alpha beta Receptor
  • Interferon alpha-beta Receptor
  • Interferon alphabeta Receptors
  • Interferon alpha Receptor
  • Interferon alpha Receptors
  • Receptor, Interferon alpha
  • Receptors, Interferon alpha
  • Receptors, Interferon alphabeta
  • Type I Interferon Receptor

Scope note

  • A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE.

History note

  • 2007(1993)

In other languages

URI

http://www.yso.fi/onto/mesh/D053633

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